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Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response

BACKGROUND: Yes-associated protein (YAP1) is frequently reported to function as an oncogene in many types of cancer, but in breast cancer results remain controversial. We set out to clarify the role of YAP1 in breast cancer by examining gene and protein expression in subgroups of patient material an...

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Detalles Bibliográficos
Autores principales: Lehn, Sophie, Tobin, Nicholas P, Sims, Andrew H, Stål, Olle, Jirström, Karin, Axelson, Håkan, Landberg, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937431/
https://www.ncbi.nlm.nih.gov/pubmed/24559095
http://dx.doi.org/10.1186/1471-2407-14-119