The methyltransferase G9a regulates HoxA9-dependent transcription in AML

Chromatin modulators are emerging as attractive drug targets, given their widespread implication in human cancers and susceptibility to pharmacological inhibition. Here we establish the histone methyltransferase G9a/EHMT2 as a selective regulator of fast proliferating myeloid progenitors with no dis...

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Detalles Bibliográficos
Autores principales: Lehnertz, Bernhard, Pabst, Caroline, Su, Le, Miller, Michelle, Liu, Feng, Yi, Lin, Zhang, Regan, Krosl, Jana, Yung, Eric, Kirschner, Jeanette, Rosten, Patty, Underhill, T. Michael, Jin, Jian, Hébert, Josée, Sauvageau, Guy, Humphries, R. Keith, Rossi, Fabio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937511/
https://www.ncbi.nlm.nih.gov/pubmed/24532712
http://dx.doi.org/10.1101/gad.236794.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937511/
https://www.ncbi.nlm.nih.gov/pubmed/24532712
http://dx.doi.org/10.1101/gad.236794.113

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