Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5′TOP mRNA translation

The mammalian target of rapamycin (mTOR) promotes cell growth and proliferation by promoting mRNA translation and increasing the protein synthetic capacity of the cell. Although mTOR globally promotes translation by regulating the mRNA 5′ cap-binding protein eIF4E (eukaryotic initiation factor 4E),...

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Detalles Bibliográficos
Autores principales: Tcherkezian, Joseph, Cargnello, Marie, Romeo, Yves, Huttlin, Edward L., Lavoie, Genevieve, Gygi, Steven P., Roux, Philippe P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937514/
https://www.ncbi.nlm.nih.gov/pubmed/24532714
http://dx.doi.org/10.1101/gad.231407.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937514/
https://www.ncbi.nlm.nih.gov/pubmed/24532714
http://dx.doi.org/10.1101/gad.231407.113

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