Cargando…

The Chiral Potential of Phenanthriplatin and Its Influence on Guanine Binding

[Image: see text] The monofunctional platinum complex cis-[Pt(NH(3))(2)Cl(Am)](+), also known as phenanthriplatin, where Am is the N-heterocyclic base phenanthridine, has promising anticancer activity. Unlike bifunctional compounds such as cisplatin, phenanthriplatin can form only one covalent bond...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnstone, Timothy C., Lippard, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937553/
https://www.ncbi.nlm.nih.gov/pubmed/24417436
http://dx.doi.org/10.1021/ja4125115