Tight Control of Hypoxia-inducible Factor-α Transient Dynamics Is Essential for Cell Survival in Hypoxia

Intracellular signaling involving hypoxia-inducible factor (HIF) controls the adaptive responses to hypoxia. There is a growing body of evidence demonstrating that intracellular signals encode temporal information. Thus, the dynamics of protein levels, as well as protein quantity and/or localization...

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Detalles Bibliográficos
Autores principales: Bagnall, James, Leedale, Joseph, Taylor, Sarah E., Spiller, David G., White, Michael R. H., Sharkey, Kieran J., Bearon, Rachel N., Sée, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937633/
https://www.ncbi.nlm.nih.gov/pubmed/24394419
http://dx.doi.org/10.1074/jbc.M113.500405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937633/
https://www.ncbi.nlm.nih.gov/pubmed/24394419
http://dx.doi.org/10.1074/jbc.M113.500405

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