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A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II

Cajal bodies are nuclear structures that are involved in biogenesis of snRNPs and snoRNPs, maintenance of telomeres and processing of histone mRNA. Recently, the SUMO isopeptidase USPL1 was identified as a component of Cajal bodies that is essential for cellular growth and Cajal body integrity. Howe...

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Detalles Bibliográficos
Autores principales: Hutten, Saskia, Chachami, Georgia, Winter, Ulrike, Melchior, Frauke, Lamond, Angus I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937775/
https://www.ncbi.nlm.nih.gov/pubmed/24413172
http://dx.doi.org/10.1242/jcs.141788