Improved site-specific recombinase-based method to produce selectable marker- and vector-backbone-free transgenic cells

PhiC31 integrase-mediated gene delivery has been extensively used in gene therapy and animal transgenesis. However, random integration events are observed in phiC31-mediated integration in different types of mammalian cells; as a result, the efficiencies of pseudo attP site integration and evaluatio...

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Detalles Bibliográficos
Autores principales: Yu, Yuan, Tong, Qi, Li, Zhongxia, Tian, Jinhai, Wang, Yizhi, Su, Feng, Wang, Yongsheng, Liu, Jun, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937794/
https://www.ncbi.nlm.nih.gov/pubmed/24577484
http://dx.doi.org/10.1038/srep04240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937794/
https://www.ncbi.nlm.nih.gov/pubmed/24577484
http://dx.doi.org/10.1038/srep04240

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