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Membranes linked by trans-SNARE complexes require lipids prone to non-bilayer structure for progression to fusion

Like other intracellular fusion events, the homotypic fusion of yeast vacuoles requires a Rab GTPase, a large Rab effector complex, SNARE proteins which can form a 4-helical bundle, and the SNARE disassembly chaperones Sec17p and Sec18p. In addition to these proteins, specific vacuole lipids are req...

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Detalles Bibliográficos
Autores principales: Zick, Michael, Stroupe, Christopher, Orr, Amy, Douville, Deborah, Wickner, William T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937803/
https://www.ncbi.nlm.nih.gov/pubmed/24596153
http://dx.doi.org/10.7554/eLife.01879