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Transcriptomics and Metabonomics Identify Essential Metabolic Signatures in Calorie Restriction (CR) Regulation across Multiple Mouse Strains

Calorie restriction (CR) has long been used to study lifespan effects and oppose the development of a broad array of age-related biological and pathological changes (increase healthspan). Yet, a comprehensive comparison of the metabolic phenotype across different genetic backgrounds to identify comm...

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Detalles Bibliográficos
Autores principales: Collino, Sebastiano, Martin, François-Pierre J., Montoliu, Ivan, Barger, Jamie L., Da Silva, Laeticia, Prolla, Tomas A., Weindruch, Richard, Kochhar, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937836/
https://www.ncbi.nlm.nih.gov/pubmed/24958256
http://dx.doi.org/10.3390/metabo3040881