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Insulin receptor compensates for IGF1R inhibition and directly induces mitogenic activity in prostate cancer cells
Hyperinsulinemia is a major complication associated with the development of insulin resistance. In addition to its normal spectrum of metabolic effects, insulin can act as a growth factor and has the ability to promote mitogenic activity. Thus, hyperinsulinemia is regarded as a potentially important...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bioscientifica Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938039/ https://www.ncbi.nlm.nih.gov/pubmed/24434591 http://dx.doi.org/10.1530/EC-13-0086 |