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MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3

BACKGROUND: Abnormal activation of the NF-κB pathway is closely related to tumorigenesis and chemoresistance. Therefore, microRNAs that possess the NF-κB inhibitory activity may provide novel targets for anti-cancer therapy. miR-26 family members have been shown to be frequently downregulated in hep...

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Detalles Bibliográficos
Autores principales: Zhao, Na, Wang, Ruizhi, Zhou, Liangji, Zhu, Ying, Gong, Jiao, Zhuang, Shi-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938074/
https://www.ncbi.nlm.nih.gov/pubmed/24565101
http://dx.doi.org/10.1186/1476-4598-13-35