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Hijacking PrP(c)-dependent signal transduction: when prions impair Aβ clearance
The cellular prion protein PrP(c) is the normal counterpart of the scrapie prion protein PrP( Sc), the main component of the infectious agent of transmissible spongiform encephalopathies. The recent discovery that PrP( c) can serve as a receptor for the amyloid beta (Aβ) peptide and relay its neurot...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938157/ https://www.ncbi.nlm.nih.gov/pubmed/24592237 http://dx.doi.org/10.3389/fnagi.2014.00025 |