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Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion

Besides its established functions in intermediary metabolism and developmental processes, the nuclear receptor peroxisome proliferator-activated receptor β/δ (PPARβ/δ) has a less defined role in tumorigenesis. In the present study, we have identified a function for PPARβ/δ in cancer cell invasion. W...

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Detalles Bibliográficos
Autores principales: Adhikary, T, Brandt, D T, Kaddatz, K, Stockert, J, Naruhn, S, Meissner, W, Finkernagel, F, Obert, J, Lieber, S, Scharfe, M, Jarek, M, Toth, P M, Scheer, F, Diederich, W E, Reinartz, S, Grosse, R, Müller-Brüsselbach, S, Müller, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938163/
https://www.ncbi.nlm.nih.gov/pubmed/23208498
http://dx.doi.org/10.1038/onc.2012.549