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Hypoxia signaling pathways in cancer metabolism: the importance of co-selecting interconnected physiological pathways

Both tumor hypoxia and dysregulated metabolism are classical features of cancer. Recent analyses have revealed complex interconnections between oncogenic activation, hypoxia signaling systems and metabolic pathways that are dysregulated in cancer. These studies have demonstrated that rather than res...

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Detalles Bibliográficos
Autores principales: Masson, Norma, Ratcliffe, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938304/
https://www.ncbi.nlm.nih.gov/pubmed/24491179
http://dx.doi.org/10.1186/2049-3002-2-3