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The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma
BACKGROUND: Paediatric high grade glioma (pHGG) is a distinct biological entity to histologically similar tumours arising in older adults, and has differing copy number profiles and driver genetic alterations. As functionally important intragenic copy number aberrations (iCNA) and fusion genes begin...
Autores principales: | Carvalho, Diana, Mackay, Alan, Bjerke, Lynn, Grundy, Richard G, Lopes, Celeste, Reis, Rui M, Jones, Chris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938307/ https://www.ncbi.nlm.nih.gov/pubmed/24548782 http://dx.doi.org/10.1186/2051-5960-2-23 |
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