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High-incidence of PTEN mutations in Chinese patients with primary small cell carcinoma of the esophagus

BACKGROUND: Primary small cell carcinoma of the esophagus (PSCCE) is a rare and aggressive tumor with poor prognosis. The aim of this study was to investigate the existence of EGFR, KRAS, PIK3CA and PTEN mutations in PSCCE. METHODS: Clinical–pathological data and paraffin-embedded specimens were col...

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Detalles Bibliográficos
Autores principales: Zhang, Zhimin, Xiao, Hualiang, Xie, Fei, Zhang, Hui, Chen, Chuan, Xiao, He, Yang, Zhenzhou, Wang, Dong, Li, Zengpeng, Wang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938318/
https://www.ncbi.nlm.nih.gov/pubmed/24422746
http://dx.doi.org/10.1186/1471-2407-14-19