Staurosporine and Extracellular Matrix Proteins Mediate the Conversion of Small Cell Lung Carcinoma Cells into a Neuron-Like Phenotype

Small cell lung carcinomas (SCLCs) represent highly aggressive tumors with an overall five-year survival rate in the range of 5 to 10%. Here, we show that four out of five SCLC cell lines reversibly develop a neuron-like phenotype on extracellular matrix constituents such as fibronectin, laminin or...

Descripción completa

Detalles Bibliográficos
Autores principales: Murmann, Tamara, Carrillo-García, Carmen, Veit, Nadine, Courts, Cornelius, Glassmann, Alexander, Janzen, Viktor, Madea, Burkhard, Reinartz, Markus, Harzen, Anne, Nowak, Michael, Perner, Sven, Winter, Jochen, Probstmeier, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938400/
https://www.ncbi.nlm.nih.gov/pubmed/24586258
http://dx.doi.org/10.1371/journal.pone.0086910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938400/
https://www.ncbi.nlm.nih.gov/pubmed/24586258
http://dx.doi.org/10.1371/journal.pone.0086910

Ejemplares similares