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Darbepoetin Alpha Reduces Oxidative Stress and Chronic Inflammation in Atherosclerotic Lesions of Apo E Deficient Mice in Experimental Renal Failure

BACKGROUND: Cardiovascular morbidity and mortality is very important in patients with chronic renal failure. This occurs even in mild impairment of renal function and may be related to oxidative stress and chronic inflammation. The nephrectomized apo E knockout mouse is an accepted model for evaluat...

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Detalles Bibliográficos
Autores principales: Arend, Nicole, Hilgers, Karl F., Campean, Valentina, Karpe, Britta, Cordasic, Nada, Klanke, Bernd, Amann, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938414/
https://www.ncbi.nlm.nih.gov/pubmed/24586350
http://dx.doi.org/10.1371/journal.pone.0088601