Abrogation of Rbpj Attenuates Experimental Autoimmune Uveoretinitis by Inhibiting IL-22-Producing CD4(+) T Cells

Experimental autoimmune uveoretinitis (EAU) is an organ-specific T cell-mediated disease induced by immunizing mice with interphotoreceptor retinoid binding protein (IRBP). Autoaggressive CD4(+) T cells are the major pathogenic population for EAU. We investigated the contribution of Notch signaling...

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Detalles Bibliográficos
Autores principales: Bhuyan, Zaied Ahmed, Asanoma, Michihito, Iwata, Akiko, Ishifune, Chieko, Maekawa, Yoichi, Shimada, Mitsuo, Yasutomo, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938452/
https://www.ncbi.nlm.nih.gov/pubmed/24586644
http://dx.doi.org/10.1371/journal.pone.0089266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938452/
https://www.ncbi.nlm.nih.gov/pubmed/24586644
http://dx.doi.org/10.1371/journal.pone.0089266

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