Cargando…

Interferon-Gamma (IFN-γ)-Mediated Retinal Ganglion Cell Death in Human Tyrosinase T Cell Receptor Transgenic Mouse

We have recently demonstrated the characterization of human tyrosinase TCR bearing h3T-A2 transgenic mouse model, which exhibits spontaneous autoimmune vitiligo and retinal dysfunction. The purpose of current study was to determine the role of T cells and IFN-γ in retina dysfunction and retinal gang...

Descripción completa

Detalles Bibliográficos
Autores principales:	Husain, Shahid, Abdul, Yasir, Webster, Christine, Chatterjee, Shilpak, Kesarwani, Pravin, Mehrotra, Shikhar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938457/ https://www.ncbi.nlm.nih.gov/pubmed/24586745 http://dx.doi.org/10.1371/journal.pone.0089392

Ejemplares similares

Blocking TCR restimulation induced necroptosis in adoptively transferred T cells improves tumor control
por: Kesarwani, Pravin, et al.
Publicado: (2016)

CD38: T Cell Immuno-Metabolic Modulator
por: Kar, Anwesha, et al.
Publicado: (2020)

CD38-NAD(+)-Sirt1 axis in T cell immunotherapy
por: Chatterjee, Shilpak, et al.
Publicado: (2019)

Dynamic Metabolism in Immune Response
por: Al-Hommrani, Mazen, et al.
Publicado: (2016)

Deletion of Pim Kinases Elevates the Cellular Levels of Reactive Oxygen Species and Sensitizes to K-Ras-Induced Cell Killing
por: Song, Jin H., et al.
Publicado: (2014)

The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases
por: DeMaio, Alexa, et al.
Publicado: (2022)

Quantitative increase in T regulatory cells enhances bone remodeling in osteogenesis imperfecta
por: Kang, In-Hong, et al.
Publicado: (2022)

High levels of interferon-gamma (IFNγ) in macrophage activation syndrome (MAS) and CXCL9 levels as a biomarker for IFNγ production in MAS
por: Bracaglia, C, et al.
Publicado: (2015)

Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones
Publicado: (1994)

IFN-gamma transgenic mice: clues to the pathogenesis of systemic lupus erythematosus?
por: Seery, John P
Publicado: (2000)

Interferon gamma (IFN-γ) disrupts energy expenditure and metabolic homeostasis by suppressing SIRT1 transcription
por: Li, Ping, et al.
Publicado: (2012)

Interferon gamma (IFNγ) +874A/T gene polymorphism in South Indian ischemic stroke patients
por: Sultana, Shehnaz, et al.
Publicado: (2011)

Serum Concentrations of Interferon Gamma (IFN-γ) in Patients with Psoriasis: Correlation with Clinical Type and Severity of the Disease
por: Kurtovic, Nermina Ovcina, et al.
Publicado: (2018)

Interferon (IFNγ) induces cell cycle arrest in RCC cell lines
por: Tate, David J, et al.
Publicado: (2013)

Hematopoietic Stem Cells as a Novel Source of Dental Tissue Cells
por: Wilson, Katie R., et al.
Publicado: (2018)

Interferon gamma (IFN-γ) negative CD4+ and CD8+ T-cells can produce immune mediators in response to viral antigens
por: Nakiboneka, Ritah, et al.
Publicado: (2019)

Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity
por: Krisnawati, Dyah Ika, et al.
Publicado: (2019)

A strategy to study tyrosinase transgenes in mouse melanocytes
por: Lavado, Alfonso, et al.
Publicado: (2005)

A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo
por: Chatterjee, Shilpak, et al.
Publicado: (2013)

CCL22 to activate Treg migration and suppress depigmentation in vitiligo
por: Eby, Jonathan M., et al.
Publicado: (2015)

Interferon gamma (IFN-γ)-mediated inflammation and the kynurenine pathway in relation to risk of hip fractures: the Hordaland Health Study
por: Apalset, E. M., et al.
Publicado: (2014)

Immunization of mice with soluble lysate of interferon gamma expressing Plasmodium berghei ANKA induces high IFN-γ production
por: Taylor, Ebenezer, et al.
Publicado: (2017)

Changes in Class I and IIb HDACs by δ-Opioid in Chronic Rat Glaucoma Model
por: Zaidi, Syed A. H., et al.
Publicado: (2020)

Reduction of Neuroinflammation by δ-Opioids Via STAT3-Dependent Pathway in Chronic Glaucoma Model
por: Husain, Shahid, et al.
Publicado: (2021)

Identification of risk factors associated with disclosure of false positive bovine tuberculosis reactors using the gamma-interferon (IFNγ) assay
por: Gormley, Eamonn, et al.
Publicado: (2013)

Intracellular Acetyl CoA Potentiates the Therapeutic Efficacy of Antitumor CD8(+) T Cells
por: Chowdhury, Snehanshu, et al.
Publicado: (2022)

Immunoproteasome Assembly: Cooperative Incorporation of Interferon γ (IFN-γ)–inducible Subunits
por: Griffin, Thomas A., et al.
Publicado: (1998)

Mouse Gamma Herpesvirus MHV-68 Induces Severe Gastrointestinal (GI) Dilatation in Interferon Gamma Receptor-Deficient Mice (IFNγR(−/−)) That Is Blocked by Interleukin-10
por: Chen, Hao, et al.
Publicado: (2018)

Anti interferon-gamma (IFNγ) monoclonal antibody treatment in a patient carrying an NLRC4 mutation and severe hemophagocytic lymphohistiocytosis
por: Bracaglia, C, et al.
Publicado: (2015)

Regulation of the interferon-gamma (IFN-γ) pathway by p63 and Δ133p53 isoform in different breast cancer subtypes
por: Mehta, Sunali Y., et al.
Publicado: (2018)

Characteristics of oligodeoxyribonucleotides that induce interferon (IFN)-α in the pig and the phenotype of the IFN-α producing cells
por: Domeika, Kristina, et al.
Publicado: (2004)

Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
por: Chakraborty, Paramita, et al.
Publicado: (2019)

MET Receptor Tyrosine Kinase Inhibition Reduces Interferon-Gamma (IFN-γ)-Stimulated PD-L1 Expression through the STAT3 Pathway in Melanoma Cells
por: Song, Kyu Young, et al.
Publicado: (2023)

Secretion of IFN-γ by Transgenic Mammary Epithelial Cells in vitro Reduced Mastitis Infection Risk in Goats
por: Liu, Ying, et al.
Publicado: (2022)

Primary demyelination in transgenic mice expressing interferon-γ
por: Horwitz, Marc S., et al.
Publicado: (1997)

In Vivo Priming of Cd4 T Cells That Produce Interleukin (Il)-2 but Not IL-4 or Interferon (Ifn)-γ, and Can Subsequently Differentiate into IL-4–Or IFN-γ–Secreting Cells
por: Wang, Xiaowen, et al.
Publicado: (2001)

Polymorphisms within the Promoter Region of the Gamma Interferon (IFN-γ) Receptor1 Gene are Associated with the Susceptibility to Chronic HBV Infection in an Iranian Population
por: Khanizadeh, Sayyad, et al.
Publicado: (2012)

NGS Evaluation of Colorectal Cancer Reveals Interferon Gamma Dependent Expression of Immune Checkpoint Genes and Identification of Novel IFNγ Induced Genes
por: Xu, Lai, et al.
Publicado: (2020)

Histone Deacetylases Regulation by δ-Opioids in Human Optic Nerve Head Astrocytes
por: Zaidi, Syed A. H., et al.
Publicado: (2020)

A Point-of-Care Based on Label-Free Interferometric Optical Detection Method to Evaluate Interferon Gamma (IFN-γ): A Correlation with the ELISA Technique
por: Heras, María Fe Laguna, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_klnocfm9g0r97li6ms8k410lf2