The Anti-Tumor Activity of a Neutralizing Nanobody Targeting Leptin Receptor in a Mouse Model of Melanoma

Environmental and genetic activation of a brain-adipocyte axis inhibits cancer progression. Leptin is the primary peripheral mediator of this anticancer effect in a mouse model of melanoma. In this study we assessed the effect of a leptin receptor antagonist on melanoma progression. Local administra...

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Detalles Bibliográficos
Autores principales: McMurphy, Travis, Xiao, Run, Magee, Daniel, Slater, Andrew, Zabeau, Lennart, Tavernier, Jan, Cao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938505/
https://www.ncbi.nlm.nih.gov/pubmed/24587106
http://dx.doi.org/10.1371/journal.pone.0089895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938505/
https://www.ncbi.nlm.nih.gov/pubmed/24587106
http://dx.doi.org/10.1371/journal.pone.0089895

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