Involvement of Sigma-1 Receptors in the Antidepressant-like Effects of Dextromethorphan

Dextromethorphan is an antitussive with a high margin of safety that has been hypothesized to display rapid-acting antidepressant activity based on pharmacodynamic similarities to the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine. In addition to binding to NMDA receptors, dextromethorphan...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Linda, Robson, Matthew J., Healy, Jason R., Scandinaro, Anna L., Matsumoto, Rae R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938562/
https://www.ncbi.nlm.nih.gov/pubmed/24587167
http://dx.doi.org/10.1371/journal.pone.0089985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938562/
https://www.ncbi.nlm.nih.gov/pubmed/24587167
http://dx.doi.org/10.1371/journal.pone.0089985

Ejemplares similares