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Anatomical Transcriptome of G Protein-Coupled Receptors Leads to the Identification of a Novel Therapeutic Candidate GPR52 for Psychiatric Disorders

Many drugs of abuse and most neuropharmacological agents regulate G protein-coupled receptors (GPCRs) in the central nervous system (CNS)_ENREF_1. The striatum, in which dopamine D1 and D2 receptors are enriched, is strongly innervated by the ventral tegmental area (VTA), which is the origin of dopa...

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Detalles Bibliográficos
Autores principales: Komatsu, Hidetoshi, Maruyama, Minoru, Yao, Shuuhei, Shinohara, Tokuyuki, Sakuma, Kensuke, Imaichi, Sachiko, Chikatsu, Tomoko, Kuniyeda, Kanako, Siu, Foo Kok, Peng, Lam Sock, Zhuo, Katherine, Mun, Lay Sock, Han, Tan Min, Matsumoto, Yoshio, Hashimoto, Tadatoshi, Miyajima, Nobuyuki, Itoh, Yasuaki, Ogi, Kazuhiro, Habata, Yugo, Mori, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938596/
https://www.ncbi.nlm.nih.gov/pubmed/24587241
http://dx.doi.org/10.1371/journal.pone.0090134