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Targeted Delivery of Erythropoietin by Transcranial Focused Ultrasound for Neuroprotection against Ischemia/Reperfusion-Induced Neuronal Injury: A Long-Term and Short-Term Study

Erythropoietin (EPO) is a neuroprotective agent against cerebral ischemia/reperfusion (I/R)-induced brain injury. However, its crossing of blood-brain barrier is limited. Focused ultrasound (FUS) sonication with microbubbles (MBs) can effectively open blood-brain barrier to boost the vascular permea...

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Detalles Bibliográficos
Autores principales: Wu, Sheng-Kai, Yang, Ming-Tao, Kang, Kai-Hsiang, Liou, Houng-Chi, Lu, Dai-Hua, Fu, Wen-Mei, Lin, Win-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938648/
https://www.ncbi.nlm.nih.gov/pubmed/24587228
http://dx.doi.org/10.1371/journal.pone.0090107