JNK Contributes to the Tumorigenic Potential of Human Cholangiocarcinoma Cells through the mTOR Pathway Regulated GRP78 Induction

Less is known about the roles of c-Jun N-terminal kinase (JNK) in cholangiocarcinoma (CCA). Here, we report that JNK exerts its oncogenic action in human CCA cells, partially due to the mammalian target of rapamycin (mTOR) pathway regulated glucose-regulated protein 78 (GRP78) induction. In human CC...

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Detalles Bibliográficos
Autores principales: Feng, Chunhong, He, Kai, Zhang, Chunyan, Su, Song, Li, Bo, Li, Yuxiao, Duan, Chun-Yan, Chen, Shaokun, Chen, Run, Liu, Youping, Li, Hong, Wei, Mei, Xia, Xianming, Dai, Rongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938720/
https://www.ncbi.nlm.nih.gov/pubmed/24587347
http://dx.doi.org/10.1371/journal.pone.0090388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938720/
https://www.ncbi.nlm.nih.gov/pubmed/24587347
http://dx.doi.org/10.1371/journal.pone.0090388

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