Rab5 Isoforms Orchestrate a “Division of Labor” in the Endocytic Network; Rab5C Modulates Rac-Mediated Cell Motility

Rab5, the prototypical Rab GTPase and master regulator of the endocytic pathway, is encoded as three differentially expressed isoforms, Rab5A, Rab5B and Rab5C. Here, we examined the differential effects of Rab5 isoform silencing on cell motility and report that Rab5C, but neither Rab5A nor Rab5B, is...

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Detalles Bibliográficos
Autores principales: Chen, Pin-I, Schauer, Kristine, Kong, Chen, Harding, Andrew R., Goud, Bruno, Stahl, Philip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938722/
https://www.ncbi.nlm.nih.gov/pubmed/24587345
http://dx.doi.org/10.1371/journal.pone.0090384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938722/
https://www.ncbi.nlm.nih.gov/pubmed/24587345
http://dx.doi.org/10.1371/journal.pone.0090384

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