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Learning from Host-Defense Peptides: Cationic, Amphipathic Peptoids with Potent Anticancer Activity

Cationic, amphipathic host defense peptides represent a promising group of agents to be developed for anticancer applications. Poly-N-substituted glycines, or peptoids, are a class of biostable, peptidomimetic scaffold that can display a great diversity of side chains in highly tunable sequences via...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Seo, Jiwon, Willingham, Stephen B., Czyzewski, Ann M., Gonzalgo, Mark L., Weissman, Irving L., Barron, Annelise E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938723/
https://www.ncbi.nlm.nih.gov/pubmed/24587350
http://dx.doi.org/10.1371/journal.pone.0090397