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Sulforaphane Inhibits Invasion via Activating ERK1/2 Signaling in Human Glioblastoma U87MG and U373MG Cells

BACKGROUND: Glioblastoma has highly invasive potential, which might result in poor prognosis and therapeutic failure. Hence, the key we study is to find effective therapies to repress migration and invasion. Sulforaphane (SFN) was demonstrated to inhibit cell growth in a variety of tumors. Here, we...

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Detalles Bibliográficos
Autores principales: Li, Chunliu, Zhou, Yan, Peng, Xiaohui, Du, Lianlian, Tian, Hua, Yang, Gaoxiang, Niu, Jing, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938755/
https://www.ncbi.nlm.nih.gov/pubmed/24587385
http://dx.doi.org/10.1371/journal.pone.0090520