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The Potential Therapeutic Effect of Guanosine after Cortical Focal Ischemia in Rats

BACKGROUND AND PURPOSE: Stroke is a devastating disease. Both excitotoxicity and oxidative stress play important roles in ischemic brain injury, along with harmful impacts on ischemic cerebral tissue. As guanosine plays an important neuroprotective role in the central nervous system, the purpose of...

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Detalles Bibliográficos
Autores principales: Hansel, Gisele, Ramos, Denise Barbosa, Delgado, Camila Aguilar, Souza, Débora Guerini, Almeida, Roberto Farina, Portela, Luis Valmor, Quincozes-Santos, André, Souza, Diogo Onofre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938812/
https://www.ncbi.nlm.nih.gov/pubmed/24587409
http://dx.doi.org/10.1371/journal.pone.0090693