False positives complicate ancient pathogen identifications using high-throughput shotgun sequencing

BACKGROUND: Identification of historic pathogens is challenging since false positives and negatives are a serious risk. Environmental non-pathogenic contaminants are ubiquitous. Furthermore, public genetic databases contain limited information regarding these species. High-throughput sequencing may...

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Detalles Bibliográficos
Autores principales: Campana, Michael G, Robles García, Nelly, Rühli, Frank J, Tuross, Noreen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938818/
https://www.ncbi.nlm.nih.gov/pubmed/24568097
http://dx.doi.org/10.1186/1756-0500-7-111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938818/
https://www.ncbi.nlm.nih.gov/pubmed/24568097
http://dx.doi.org/10.1186/1756-0500-7-111

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