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False positives complicate ancient pathogen identifications using high-throughput shotgun sequencing
BACKGROUND: Identification of historic pathogens is challenging since false positives and negatives are a serious risk. Environmental non-pathogenic contaminants are ubiquitous. Furthermore, public genetic databases contain limited information regarding these species. High-throughput sequencing may...
Autores principales: | Campana, Michael G, Robles García, Nelly, Rühli, Frank J, Tuross, Noreen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938818/ https://www.ncbi.nlm.nih.gov/pubmed/24568097 http://dx.doi.org/10.1186/1756-0500-7-111 |
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