Inferring Regulatory Networks by Combining Perturbation Screens and Steady State Gene Expression Profiles

Reconstructing transcriptional regulatory networks is an important task in functional genomics. Data obtained from experiments that perturb genes by knockouts or RNA interference contain useful information for addressing this reconstruction problem. However, such data can be limited in size and/or a...

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Detalles Bibliográficos
Autores principales: Shojaie, Ali, Jauhiainen, Alexandra, Kallitsis, Michael, Michailidis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938831/
https://www.ncbi.nlm.nih.gov/pubmed/24586224
http://dx.doi.org/10.1371/journal.pone.0082393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938831/
https://www.ncbi.nlm.nih.gov/pubmed/24586224
http://dx.doi.org/10.1371/journal.pone.0082393

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