Cargando…

Gadd45a deletion aggravates hematopoietic stem cell dysfunction in ATM-deficient mice

Ataxia telangiectasia mutated (ATM) kinase plays an essential role in the maintenance of genomic stability. ATM-deficient (ATM(−/−)) mice exhibit hematopoietic stem cell (HSC) dysfunction and a high incidence of lymphoma. Gadd45a controls cell cycle arrest, apoptosis and DNA repair, and is involved...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yulin, Yang, Runan, Guo, Peng, Ju, Zhenyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938854/ https://www.ncbi.nlm.nih.gov/pubmed/24474198 http://dx.doi.org/10.1007/s13238-013-0017-9

Ejemplares similares

Gadd45β and Gadd45γ are critical for regulating autoimmunity
por: Liu, Lin, et al.
Publicado: (2005)

Cytokine-Regulated GADD45G Induces Differentiation and Lineage Selection in Hematopoietic Stem Cells
por: Thalheimer, Frederic B., et al.
Publicado: (2014)

Double-edged Gadd45
por: Powell, Kendall
Publicado: (2005)

Gadd45 in stress signaling
por: Liebermann, Dan A, et al.
Publicado: (2008)

GADD45A and GADD45B as Novel Biomarkers Associated with Chromatin Regulators in Renal Ischemia-Reperfusion Injury
por: Xie, Ming, et al.
Publicado: (2023)

Gadd45b deficiency promotes premature senescence and skin aging
por: Magimaidas, Andrew, et al.
Publicado: (2016)

GADD45a and GADD45b Genes in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients
por: Li, Ruei-Nian, et al.
Publicado: (2019)

GADD45B mediates podocyte injury in zebrafish by activating the ROS-GADD45B-p38 pathway
por: Chen, Z, et al.
Publicado: (2016)

Gadd45 stress sensors in suppression of leukemia
por: Wiest, David L.
Publicado: (2018)

Gadd45a deficiency accelerates BCR-ABL driven chronic myelogenous leukemia
por: Mukherjee, Kaushiki, et al.
Publicado: (2017)

DNA‐damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival
por: Wingert, Susanne, et al.
Publicado: (2016)

GADD45A Does Not Promote DNA Demethylation
por: Jin, Seung-Gi, et al.
Publicado: (2008)

Gadd45a promotes DNA demethylation through TDG
por: Li, Zheng, et al.
Publicado: (2015)

Ribosomal protein S7 regulates arsenite-induced GADD45α expression by attenuating MDM2-mediated GADD45α ubiquitination and degradation
por: Gao, Ming, et al.
Publicado: (2013)

Deficiency in TR4 nuclear receptor abrogates Gadd45a expression and increases cytotoxicity induced by ionizing radiation
por: Yan, Shian-Jang, et al.
Publicado: (2012)

Abnormal expression of GADD45B in human colorectal carcinoma
por: Wang, Lisha, et al.
Publicado: (2012)

GADD45a physically and functionally interacts with TET1
por: Kienhöfer, Sabine, et al.
Publicado: (2015)

Down-regulation of GADD45A enhances chemosensitivity in melanoma
por: Liu, Jia, et al.
Publicado: (2018)

The role of Gadd45b in neurologic and neuropsychiatric disorders: An overview
por: Shen, Xiao-yue, et al.
Publicado: (2022)

Gadd45g initiates embryonic stem cell differentiation and inhibits breast cell carcinogenesis
por: Zhang, Xinbao, et al.
Publicado: (2021)

Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia
por: Duecker, Ruth, et al.
Publicado: (2019)

Methylation mediated Gadd45β enhanced the chemosensitivity of hepatocellular carcinoma by inhibiting the stemness of liver cancer cells
por: Hou, Xiao-Juan, et al.
Publicado: (2017)

Gadd45α: A Novel Diabetes-Associated Gene Potentially Linking Diabetic Cardiomyopathy and Baroreflex Dysfunction
por: Wang, Ning, et al.
Publicado: (2012)

IL-12p40 deletion aggravates lipopolysaccharide-induced cardiac dysfunction in mice
por: Liu, Menglin, et al.
Publicado: (2022)

Gadd45a Is an RNA Binding Protein and Is Localized in Nuclear Speckles
por: Sytnikova, Yuliya A., et al.
Publicado: (2011)

Mutation analysis of the Gadd45 gene at exon 4 in atypical fibroxanthoma
por: Sakamoto, Akio, et al.
Publicado: (2009)

The role of D-GADD45 in oxidative, thermal and genotoxic stress resistance
por: Moskalev, Alexey, et al.
Publicado: (2012)

The expression and clinical significance of GADD45A in breast cancer patients
por: Wang, Junnan, et al.
Publicado: (2018)

Loss of Gadd45b accelerates BCR-ABL-driven CML
por: Sha, Xiaojin, et al.
Publicado: (2018)

Role of D-GADD45 in JNK-Dependent Apoptosis and Regeneration in Drosophila
por: Camilleri-Robles, Carlos, et al.
Publicado: (2019)

Mathematical modelling of the role of GADD45β in the pathogenesis of multiple myeloma
por: Zhang, Yao, et al.
Publicado: (2020)

Azacitidine regulates DNA methylation of GADD45γ in myelodysplastic syndromes
por: Yang, Yanli, et al.
Publicado: (2020)

Regulation of dopamine-dependent transcription and cocaine action by Gadd45b
por: Zipperly, Morgan E., et al.
Publicado: (2020)

Growth arrest and DNA damage-inducible proteins (GADD45) in psoriasis
por: Rodríguez-Jiménez, Pedro, et al.
Publicado: (2021)

Regulation of neuronal plasticity by the DNA repair associated Gadd45 proteins
por: Brito, David V.C., et al.
Publicado: (2022)

GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells
por: Schüle, Katrin M., et al.
Publicado: (2019)

GADD45α drives brown adipose tissue formation through upregulating PPARγ in mice
por: You, Wenjing, et al.
Publicado: (2020)

Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer
por: Jia, Ming, et al.
Publicado: (2016)

Nucleolin links to arsenic-induced stabilization of GADD45α mRNA
por: Zhang, Yadong, et al.
Publicado: (2006)

Abnormal Levels of Gadd45alpha in Developing Neocortex Impair Neurite Outgrowth
por: Sarkisian, Matthew R., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_4bmqj53po5v4h4lvgicgah3vt7