Aging promotes pro-fibrotic matrix production and increases fibrocyte recruitment during acute lung injury

Fibrotic lung diseases increase with age. Previously we determined that senescence increases tissue expression of fibronectin EDA (Fn-EDA) and decreases fibroblast expression of Thy-1, and that fibrocytes contribute to fibrosis following bleomycin-induced lung injury in mice. In this study we hypoth...

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Detalles Bibliográficos
Autores principales: Sueblinvong, Viranuj, Neveu, Wendy A., Neujahr, David C., Mills, Stephen T., Rojas, Mauricio, Roman, Jesse, Guidot, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939026/
https://www.ncbi.nlm.nih.gov/pubmed/24596659
http://dx.doi.org/10.4236/abb.2014.51004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939026/
https://www.ncbi.nlm.nih.gov/pubmed/24596659
http://dx.doi.org/10.4236/abb.2014.51004

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