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Aging promotes pro-fibrotic matrix production and increases fibrocyte recruitment during acute lung injury
Fibrotic lung diseases increase with age. Previously we determined that senescence increases tissue expression of fibronectin EDA (Fn-EDA) and decreases fibroblast expression of Thy-1, and that fibrocytes contribute to fibrosis following bleomycin-induced lung injury in mice. In this study we hypoth...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939026/ https://www.ncbi.nlm.nih.gov/pubmed/24596659 http://dx.doi.org/10.4236/abb.2014.51004 |