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Meta-Analysis of Gene Level Tests for Rare Variant Association

The vast majority of connections between complex disease and common genetic variants were identified through meta-analysis, a powerful approach that enables large sample sizes while protecting against common artifacts due to population structure, repeated small sample analyses, and/or limitations wi...

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Detalles Bibliográficos
Autores principales: Liu, Dajiang J., Peloso, Gina M., Zhan, Xiaowei, Holmen, Oddgeir L., Zawistowski, Matthew, Feng, Shuang, Nikpay, Majid, Auer, Paul L., Goel, Anuj, Zhang, He, Peters, Ulrike, Farrall, Martin, Orho-Melander, Marju, Kooperberg, Charles, McPherson, Ruth, Watkins, Hugh, Willer, Cristen J., Hveem, Kristian, Melander, Olle, Kathiresan, Sekar, Abecasis, Gonçalo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939031/
https://www.ncbi.nlm.nih.gov/pubmed/24336170
http://dx.doi.org/10.1038/ng.2852