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Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism

The mechanisms that coordinate the final mitotic divisions of terminally differentiated bone marrow erythroid cells with components of their structural and functional maturation program remain largely undefined. We previously identified phenotypes resembling those found in early-stage myelodysplasti...

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Detalles Bibliográficos
Autores principales: Xu, Yanfei, Swartz, Kelsey L., Siu, Ka Tat, Bhattacharyya, Mitra, Minella, Alex C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939062/
https://www.ncbi.nlm.nih.gov/pubmed/23873023
http://dx.doi.org/10.1038/onc.2013.289