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A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients

BACKGROUND: Tumor-associated macrophages (TAMs) are classified into two major phenotypes, M1 and M2. M1 TAMs suppress cancer progression, while M2 TAMs promote it. However, little is known regarding the role of TAMs in the development of ovarian cancer. Here, we investigated the relationship between...

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Detalles Bibliográficos
Autores principales: Zhang, Meiying, He, Yifeng, Sun, Xiangjun, Li, Qing, Wang, Wenjing, Zhao, Aimin, Di, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939626/
https://www.ncbi.nlm.nih.gov/pubmed/24507759
http://dx.doi.org/10.1186/1757-2215-7-19