Cargando…

A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients

BACKGROUND: Tumor-associated macrophages (TAMs) are classified into two major phenotypes, M1 and M2. M1 TAMs suppress cancer progression, while M2 TAMs promote it. However, little is known regarding the role of TAMs in the development of ovarian cancer. Here, we investigated the relationship between...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Meiying, He, Yifeng, Sun, Xiangjun, Li, Qing, Wang, Wenjing, Zhao, Aimin, Di, Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939626/ https://www.ncbi.nlm.nih.gov/pubmed/24507759 http://dx.doi.org/10.1186/1757-2215-7-19

Ejemplares similares

High MUC2 Expression in Ovarian Cancer Is Inversely Associated with the M1/M2 Ratio of Tumor-Associated Macrophages and Patient Survival Time
por: He, Yi-feng, et al.
Publicado: (2013)

Risk prediction model for epithelial ovarian cancer using molecular markers and clinical characteristics
por: Zhang, Meiying, et al.
Publicado: (2015)

TP53 mutation-mediated genomic instability induces the evolution of chemoresistance and recurrence in epithelial ovarian cancer
por: Zhang, Meiying, et al.
Publicado: (2017)

M3 Macrophages Stop Division of Tumor Cells In Vitro and Extend Survival of Mice with Ehrlich Ascites Carcinoma
por: Kalish, Sergey, et al.
Publicado: (2017)

Role of M1-polarized tumor-associated macrophages in the prognosis of advanced ovarian cancer patients
por: Macciò, Antonio, et al.
Publicado: (2020)

The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
por: Ma, Junliang, et al.
Publicado: (2010)

Interferon-γ and celecoxib inhibit lung-tumor growth through modulating M2/M1 macrophage ratio in the tumor microenvironment
por: Ren, Fuqiang, et al.
Publicado: (2014)

Integrated analysis of the M2 macrophage-related signature associated with prognosis in ovarian cancer
por: Peng, Caijiao, et al.
Publicado: (2022)

d-lactate modulates M2 tumor-associated macrophages and remodels immunosuppressive tumor microenvironment for hepatocellular carcinoma
por: Han, Shulan, et al.
Publicado: (2023)

Tumor-associated M2 macrophages in the immune microenvironment influence the progression of renal clear cell carcinoma by regulating M2 macrophage-associated genes
por: Zhang, Xiaoxu, et al.
Publicado: (2023)

CircITGB6 promotes ovarian cancer cisplatin resistance by resetting tumor-associated macrophage polarization toward the M2 phenotype
por: Li, Han, et al.
Publicado: (2022)

Identification of Genes Associated with Prognosis and Immunotherapy Prediction in Triple-Negative Breast Cancer via M1/M2 Macrophage Ratio
por: Liu, Jianyu, et al.
Publicado: (2023)

Identification and validation of novel biomarkers affecting bladder cancer immunotherapy via machine learning and its association with M2 macrophages
por: Wang, Junkang, et al.
Publicado: (2022)

Tumor-Associated Macrophages Contribute to Tumor Progression in Ovarian Cancer
por: Colvin, Emily K.
Publicado: (2014)

Metabolic Reprogramming in Tumor-Associated Macrophages in the Ovarian Tumor Microenvironment
por: Kumar, Sudhir, et al.
Publicado: (2022)

Umbelliprenin Increases the M1/M2 Ratio of Macrophage Polarization and Improves the M1 Macrophage Activity in THP-1 Cells Cocultured with AGS Cells
por: Bahrami, MohammadTaher, et al.
Publicado: (2021)

M1/M2 macrophages and associated mechanisms in congenital bicuspid aortic valve stenosis
por: WANG, RUI, et al.
Publicado: (2014)

Attenuated Listeria monocytogenes reprograms M2-polarized tumor-associated macrophages in ovarian cancer leading to iNOS-mediated tumor cell lysis
por: Lizotte, Patrick H, et al.
Publicado: (2014)

Tumor microenvironment remodeling and tumor therapy based on M2-like tumor associated macrophage-targeting nano-complexes
por: Han, Shulan, et al.
Publicado: (2021)

Cardamonin suppresses pro-tumor function of macrophages by decreasing M2 polarization on ovarian cancer cells via mTOR inhibition
por: Chen, Huajiao, et al.
Publicado: (2022)

Targeting crosstalk of STAT3 between tumor-associated M2 macrophages and Tregs in colorectal cancer
por: Huang, Lili, et al.
Publicado: (2023)

Tumor-Associated Macrophages and Ovarian Cancer: Implications for Therapy
por: Schweer, David, et al.
Publicado: (2022)

M1(hot) tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer
por: Garrido-Martin, Eva M, et al.
Publicado: (2020)

Prognostic Implication of M2 Macrophages Are Determined by the Proportional Balance of Tumor Associated Macrophages and Tumor Infiltrating Lymphocytes in Microsatellite-Unstable Gastric Carcinoma
por: Kim, Kyung-Ju, et al.
Publicado: (2015)

Metformin prevents cancer metastasis by inhibiting M2-like polarization of tumor associated macrophages
por: Ding, Ling, et al.
Publicado: (2015)

Fasting inhibits colorectal cancer growth by reducing M2 polarization of tumor-associated macrophages
por: Sun, Pengfei, et al.
Publicado: (2017)

Integrated microRNA and mRNA signatures associated with overall survival in epithelial ovarian cancer
por: Lopacinska-Jørgensen, Joanna, et al.
Publicado: (2021)

NapM enhances the survival of Mycobacterium tuberculosis under stress and in macrophages
por: Liu, Yu, et al.
Publicado: (2019)

TRAIL promotes the polarization of human macrophages toward a proinflammatory M1 phenotype and is associated with increased survival in cancer patients with high tumor macrophage content
por: Gunalp, Sinem, et al.
Publicado: (2023)

Targeting and repolarizing M2-like tumor-associated macrophage-mediated MR imaging and tumor immunotherapy by biomimetic nanoparticles
por: Chong, Lijuan, et al.
Publicado: (2023)

CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway
por: Bai, Yihan, et al.
Publicado: (2020)

Vinblastine resets tumor-associated macrophages toward M1 phenotype and promotes antitumor immune response
por: Wang, Yi-Na, et al.
Publicado: (2023)

M1 polarization enhances the antitumor activity of chimeric antigen receptor macrophages in solid tumors
por: Huo, Yi, et al.
Publicado: (2023)

Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes
por: Luo, Zhengkang, et al.
Publicado: (2022)

Gemcitabine Recruits M2-Type Tumor-Associated Macrophages into the Stroma of Pancreatic Cancer
por: Bulle, Ashenafi, et al.
Publicado: (2020)

Prognostic value of intratumoral lymphocyte-to-monocyte ratio and M0 macrophage enrichment in tumor immune microenvironment of melanoma
por: Jairath, Neil K, et al.
Publicado: (2020)

Tumor-infiltrating M2 macrophages driven by specific genomic alterations are associated with prognosis in bladder cancer
por: Xue, Yongping, et al.
Publicado: (2019)

TGF-β-induced IRAK-M Expression in Tumor Associated Macrophages Regulates Lung Tumor Growth
por: Standiford, Theodore J., et al.
Publicado: (2011)

Infiltration of M2 Tumor-Associated Macrophages in Oral Squamous Cell Carcinoma Correlates with Tumor Malignancy
por: Mori, Kazumasa, et al.
Publicado: (2011)

Intrahepatic cholangiocarcinoma induced M2-polarized tumor-associated macrophages facilitate tumor growth and invasiveness
por: Yuan, Hui, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_h65vtllh0gfhs1bqb3j0it2891