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Do randomized clinical trials with inadequate blinding report enhanced placebo effects for intervention groups and nocebo effects for placebo groups?

BACKGROUND: Studies suggest that expectations powerfully shape clinical outcomes. For subjective outcomes in adequately blinded trials, health improvements are substantial and largely explained by non-specific factors. The objective of this study was to investigate if unblinding in randomized contro...

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Detalles Bibliográficos
Autores principales: Feys, Frederik, Bekkering, Geertruida E, Singh, Kavita, Devroey, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939643/
https://www.ncbi.nlm.nih.gov/pubmed/24555576
http://dx.doi.org/10.1186/2046-4053-3-14