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Do randomized clinical trials with inadequate blinding report enhanced placebo effects for intervention groups and nocebo effects for placebo groups?
BACKGROUND: Studies suggest that expectations powerfully shape clinical outcomes. For subjective outcomes in adequately blinded trials, health improvements are substantial and largely explained by non-specific factors. The objective of this study was to investigate if unblinding in randomized contro...
Autores principales: | Feys, Frederik, Bekkering, Geertruida E, Singh, Kavita, Devroey, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939643/ https://www.ncbi.nlm.nih.gov/pubmed/24555576 http://dx.doi.org/10.1186/2046-4053-3-14 |
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