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Population Pharmacokinetics and Pharmacokinetic-Pharmacodynamic Relationships of Methadone in a Sample of Iranian (Mazandarani) Opiate Users Undergoing Methadone Maintenance Treatment
Objective: To investigate the pharmacokinetics (PK) and PK- pharmacodynamic (PD) relationship of methadone in a cohort of outpatients undergoing methadone maintenance treatment (MMT). Methods: Sixty male patients undergoing MMT with a mean ±SD methadone daily dosage of 58 ± 34 mg were enrolled in th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mazandaran University of Medical Sciences
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939965/ https://www.ncbi.nlm.nih.gov/pubmed/24644447 |