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Duplex quantitative Reverse-Transcriptase PCR for simultaneous assessment of drug activity against Leishmania intracellular amastigotes and their host cells()

Currently available drugs for treatment of Leishmania infections are highly toxic and drug resistance to first line therapies has been observed. New, safer and more effective drugs are urgently needed to improve clinical resolution of the disease and reduce the risks associated with it. High-through...

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Detalles Bibliográficos
Autores principales: van den Bogaart, Erika, Schoone, Gerard J., Adams, Emily R., Schallig, Henk D.F.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940078/
https://www.ncbi.nlm.nih.gov/pubmed/24596664
http://dx.doi.org/10.1016/j.ijpddr.2013.11.001