Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motor

ATPases of the AAA+ superfamily are large oligomeric molecular machines that remodel their substrates by converting the energy from ATP hydrolysis into mechanical force. This study focuses on the molecular chaperone ClpB, the bacterial homologue of Hsp104, which reactivates aggregated proteins under...

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Detalles Bibliográficos
Autores principales: Zeymer, Cathleen, Barends, Thomas R. M., Werbeck, Nicolas D., Schlichting, Ilme, Reinstein, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940203/
https://www.ncbi.nlm.nih.gov/pubmed/24531492
http://dx.doi.org/10.1107/S1399004713030629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940203/
https://www.ncbi.nlm.nih.gov/pubmed/24531492
http://dx.doi.org/10.1107/S1399004713030629

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