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Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis

BACKGROUND: Fragile X syndrome and tuberous sclerosis are genetic syndromes that both have a high rate of comorbidity with autism spectrum disorder (ASD). Several lines of evidence suggest that these two monogenic disorders may converge at a molecular level through the dysfunction of activity-depend...

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Detalles Bibliográficos
Autores principales: Kong, Sek Won, Sahin, Mustafa, Collins, Christin D, Wertz, Mary H, Campbell, Malcolm G, Leech, Jarrett D, Krueger, Dilja, Bear, Mark F, Kunkel, Louis M, Kohane, Isaac S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940253/
https://www.ncbi.nlm.nih.gov/pubmed/24564913
http://dx.doi.org/10.1186/2040-2392-5-16