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Exogenous norepinephrine attenuates the efficacy of sunitinib in a mouse cancer model

BACKGROUND: Sunitinib alone exhibits satisfactory efficacy in several mouse homografts and xenografts but unsatisfactory efficacy in many kinds of solid tumors in clinic. Different from animals, receiving a diagnosis of cancer impacts chronic stress on patients. Here, we examine whether norepinephri...

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Detalles Bibliográficos
Autores principales: Deng, Guo-Hua, Liu, Jie, Zhang, Jie, Wang, Ying, Peng, Xing-Chen, Wei, Yu-Quan, Jiang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940302/
https://www.ncbi.nlm.nih.gov/pubmed/24555849
http://dx.doi.org/10.1186/1756-9966-33-21