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Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung

Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome, a devastating inflammatory condition charact...

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Detalles Bibliográficos
Autores principales: Lucas, C D, Dorward, D A, Tait, M A, Fox, S, Marwick, J A, Allen, K C, Robb, C T, Hirani, N, Haslett, C, Duffin, R, Rossi, A G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940382/
https://www.ncbi.nlm.nih.gov/pubmed/24280938
http://dx.doi.org/10.1038/mi.2013.102