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Measurement Errors in Polymerase Chain Reaction Are a Confounding Factor for a Correct Interpretation of 5-HTTLPR Polymorphism Effects on Lifelong Premature Ejaculation: A Critical Analysis of a Previously Published Meta-Analysis of Six Studies

OBJECTIVE: To analyze a recently published meta-analysis of six studies on 5-HTTLPR polymorphism and lifelong premature ejaculation (PE). METHODS: Calculation of fraction observed and expected genotype frequencies and Hardy Weinberg equilibrium (HWE) of cases and controls. LL,SL and SS genotype freq...

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Detalles Bibliográficos
Autores principales: Janssen, Paddy K. C., Olivier, Berend, Zwinderman, Aeilko H., Waldinger, Marcel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940425/
https://www.ncbi.nlm.nih.gov/pubmed/24595335
http://dx.doi.org/10.1371/journal.pone.0088031