Arginine 199 and Leucine 208 Have Key Roles in the Control of Adenosine A(2A) Receptor Signalling Function

One successful approach to obtaining high-resolution crystal structures of G-protein coupled receptors is the introduction of thermostabilising mutations within the receptor. This technique allows the generation of receptor constructs stabilised into different conformations suitable for structural s...

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Detalles Bibliográficos
Autores principales: Bertheleme, Nicolas, Strege, Annette, Bunting, Sorrel E., Dowell, Simon J., Byrne, Bernadette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940607/
https://www.ncbi.nlm.nih.gov/pubmed/24595172
http://dx.doi.org/10.1371/journal.pone.0089613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940607/
https://www.ncbi.nlm.nih.gov/pubmed/24595172
http://dx.doi.org/10.1371/journal.pone.0089613

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