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Arginine 199 and Leucine 208 Have Key Roles in the Control of Adenosine A(2A) Receptor Signalling Function
One successful approach to obtaining high-resolution crystal structures of G-protein coupled receptors is the introduction of thermostabilising mutations within the receptor. This technique allows the generation of receptor constructs stabilised into different conformations suitable for structural s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940607/ https://www.ncbi.nlm.nih.gov/pubmed/24595172 http://dx.doi.org/10.1371/journal.pone.0089613 |